The manager is unhappy the hosts have had two more days to prepare for Saturdays FA Cup third round clash at Anfield.
Wolves drew 1-1 at Aston Villa on Wednesday after Liverpool lost 3-1 at Brentford 48 hours earlier.
They have had five days, I prefer not to repeat it. We have to be ready. Despite the situation we have to prepare for the cup in the best way we can, he said.
Its very important but Liverpool have had two days more to prepare and rest.
We have another match in three days [after] with the Carabao Cup. We have to be able to do a good match against one of the best teams in the world.
Its not our responsibility, we have to play, I have commented it is different in the league. In the cup you dont have a second chance, its not balanced but its not our responsibility.
Maybe we can work normally because a lot of players have to recuperate but tomorrow we will be ready to try to beat one of the best teams in the world. They have an incredible squad. Itll be a good challenge for us.
Daniel Podence and Pedro Neto remain out for Wolves with Lopetegui expected to make changes and new striker Matheus Cunha is in the running to start.
No new signings are expected before the Anfield trip and skipper Ruben Neves has again been linked with Barcelona, but Lopetegui insists his only concern is reinforcements.
We are not thinking about the possibility about moving out players, we are thinking about the possibility of bringing them in, he said.
I understand the interest in the transfer window but our interest is only for the match. Ruben Neves is a fantastic player, he is a Wolves player and he will continue being a Wolves player.
Ask me 100 times, its the same. Our focus is on the match tomorrow.