United&aposs hopes of progressing to the knockout rounds of the Champions League took a major blow in midweek following a 4-3 defeat against FC Copenhagen and a win against Luton before the international break is required.
Erik ten Hag&aposs side have a strong record against teams towards the bottom half of the table and Luton were the favourites to be relegated at the start of the season, although they did draw against Liverpool at the weekend.
Regarding the team news, Marcus Rashford&aposs red card in the Champions League has no impact on his availability in the league and Jonny Evans, who went off injured against Copenhagen, has been ruled out of the match.
Our writers have had their say on how United should line up…
United were so good when it was 11 v 11 in Copenhagen the only change should be enforced. Raphael Varane is the obvious replacement for Jonny Evans.
Scott McTominay has done decently of late, Christian Eriksen&aposs creativity will be needed against what is bound to be a reticent Luton, Rashford and Aaron Wan-Bissaka showed promise down the right, Alejandro Garnacho has produced more mature performances from the start, Bruno Fernandes had telling impacts in midweek and Rasmus Hojlund was back among the goals.
Another midweek defeat does not mean United should rip up and start again. Evans misses out due to injury and Reguilon has to be worth a go on the left again.
Mount is yet to shine in a United shirt and this is the type of game in which he should. He doesn&apost deserve to start on current form but he needs another opportunity to show why Ten Hag wanted him so much.
The front three linked up really well at times against Copenhagen and there is no reason for any changes there.
Evans has been ruled out of this match, which means there is a choice to make between Lindelof and Varane. The Frenchman was awful from the bench against Copenhagen but should get another chance to play here.