United suffered two fresh injury blows before the November break had even kicked off, having seen Danish duo Rasmus Hojlund and Christian Eriksen pick up knocks in the 1-0 win over Luton Town. That misery was compounded last Friday as Ten Hag saw both Marcus Rashford and Andre Onana forced off for their respective countries.
The November international fixtures are now coming to a close and Ten Hag is starting to welcome players back to Manchester. On Sunday, they head to Goodison Park to face Everton in the Premier League and the Reds boss will hope to have a few key players returning to fitness.
MEN Sport has rounded up the injury updates we know so far.
Injury: Unknown
What we know: Rashford was substituted after colliding with Trent Alexander-Arnold during England&aposs win over Malta on Friday. Gareth Southgate insisted the forward was &aposprobably okay&apos and he came off the bench for six minutes during Monday&aposs 1-1 draw in North Macedonia.
Potential return date: November 26 vs Everton
Injury: Unspecified
What we know: Onana received treatment on the pitch during Cameroon&aposs victory over Mauritius. The goalkeeper has been left out of the squad to face Libya on Tuesday. There has been no prognosis as of yet.
Potential return date: Unknown
Injury: Hamstring
What we know: Hojlund was forced off with a hamstring issue against Luton Town. The 20-year-old withdrew from international duty and has remained in Manchester to begin his rehabilitation, with the club confirming they hope to have him back before the end of November.
Potential return date: November 26 vs Everton
Injury: Knee
What we know: The midfielder also came off in the victory over Luton and withdrew from the Denmark squad due to a knee issue. The club confirmed last week that Eriksen will be out for &aposaround a month&apos.
Potential return date: December 12 vs Bayern Munich
Injury: Hamstring
What we know: The Brazilian suffered the complaint during the Carabao Cup defeat to Newcastle. Ten Hag does not expect to have the Brazilian back until the new year.
Potential return date: January
Injury: Illness
What we know: Wan-Bissaka pulled out of the Luton squad with illness but it is not thought to be a major problem.
Potential return date: November 26 vs Everton
Injury: Muscular
What we know: Ten Hag ruled out any return for Shaw until after the international break so all eyes will be on the full-back prior to the clash with Everton.
Potential return date: November 26 vs Everton
Injury: Foot
What we know: Martinez is recovering from surgery on his foot, following a recurrence of the issue suffered against Sevilla last season. Like Casemiro, Ten Hag does not expect to have the defender back before Christmas.
Potential return date: January
Injury: Knee
What we know: The defender has managed to return to individual training after undergoing surgery but a return date has not been set. It is hoped he will be back before the new year.
Potential return date: Unknown
Injury: Knee